Veterinarian Opinions on NAD+ for Dogs: Is It Right for Your Pet?

Ozzy Fitoria

As pet owners, we always strive to provide the best possible care for our furry companions. With advancements in veterinary medicine and a growing understanding of canine health, new supplements and therapies are constantly emerging. One such area of interest is Nicotinamide Adenine Dinucleotide (NAD+) and its potential benefits for dogs. This article delves into veterinarian opinions on NAD+ supplementation for dogs, exploring its role, potential benefits, and considerations for pet owners.

NAD+ is a crucial coenzyme found in all living cells, playing a vital role in numerous biological processes, including energy production, DNA repair, and cellular signaling. NAD+ falls with age in multiple tissues studied in rodents, and in blood in humans. No canine aging study has been published, so the same cannot be said from direct dog data. Understanding the potential of NAD+ to support canine health is paramount for responsible pet ownership.

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The Science Behind NAD+ and Canine Health

NAD+ is essential for cellular energy production within the mitochondria, often referred to as the powerhouse of the cell. It acts as a key player in metabolic processes, helping convert nutrients into energy that fuels various bodily functions. Furthermore, NAD+ is involved in DNA repair mechanisms, helping maintain the integrity of the genetic code. It also participates in cellular signaling pathways, influencing gene expression and cell communication. NAD+ falls with age in multiple tissues studied in rodents, and in blood in humans. No canine aging study has been published, so the same cannot be said from direct dog data.

Several studies have explored the potential benefits of NAD+ supplementation in animals. While research specifically focused on dogs is still emerging, studies in other species have shown that boosting NAD+ levels can improve mitochondrial function, enhance cellular energy, promote healthy aging, and support overall health. These findings have sparked interest among veterinarians and pet owners alike, leading to further investigation into the potential applications of NAD+ supplementation in canine health. Veterinarians are closely monitoring the research on NAD+ and its effects on animals, including dogs.

Potential Benefits of NAD+ Supplementation for Dogs: Veterinarian Insights

Veterinarians are cautiously optimistic about the potential benefits of NAD+ supplementation for dogs, particularly in addressing age-related health concerns. Some of the potential benefits being explored include:

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  • Supporting Cognitive Function: As dogs age, they may experience cognitive decline, characterized by memory loss, disorientation, and changes in behavior. NAD+ helps maintain cellular energy and supports neuronal function, potentially mitigating some of these age-related cognitive changes.
  • Supporting Cellular Systems: By supporting cellular repair and energy production, NAD+ supplementation supports the cellular systems described above; no effect on aging has been demonstrated in dogs. It supports healthy aging by promoting better metabolism.
  • Supporting Energy Levels and Vitality: NAD+ is crucial for energy production, and supplementing with NAD+ precursors may help boost energy levels and combat fatigue in aging dogs, allowing them to remain active and engaged.
  • Supporting Metabolic Health: NAD+ plays a key role in regulating metabolism. Supplementation may help support healthy blood sugar levels and insulin sensitivity in dogs, promoting overall metabolic health.

It's important to note that while these potential benefits are promising, more research is needed to fully understand the long-term effects of NAD+ supplementation in dogs. Veterinarians emphasize the importance of consulting with a qualified veterinary professional before starting any new supplement regimen for your pet.

Considerations and Cautions: A Veterinarian's Perspective

While NAD+ supplementation shows promise, veterinarians stress the importance of approaching it with caution and considering several factors:

  • Quality and Safety: Not all NAD+ supplements are created equal. It's crucial to choose high-quality products from reputable manufacturers that have been tested for purity and potency. Look for supplements that have undergone third-party testing to ensure their safety and efficacy.
  • Dosage and Administration: The optimal dosage of NAD+ for dogs may vary depending on their size, age, and health condition. It's essential to consult with a veterinarian to determine the appropriate dosage and administration method for your pet.
  • Potential Side Effects: While NAD+ is generally considered safe, some dogs may experience mild side effects, such as gastrointestinal upset. It's important to monitor your dog closely for any adverse reactions and discontinue use if necessary.
  • Interactions with Medications: NAD+ supplements may interact with certain medications. It's crucial to inform your veterinarian about all medications your dog is taking before starting NAD+ supplementation.

Veterinarians also emphasize that NAD+ supplementation should not be considered a replacement for conventional veterinary care. It's essential to continue providing your dog with a balanced diet, regular exercise, and routine veterinary checkups. Considering the impact of cellular energy on overall health, it's important to discuss all options with your vet.

Ultimately, the decision of whether or not to supplement your dog's diet with NAD+ should be made in consultation with a qualified veterinarian who can assess your pet's individual needs and health status. Learn more about NAD+

References

[1] Yoshino, M., Mills, K. F., Yoon, M. J., & Imai, S. I. (2018). Nicotinamide mononucleotide, a key NAD+ intermediate, treats glucose intolerance by upregulating Nmnat1. Cell metabolism, 14(4), 528-536.

[2] Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic potential of nicotinamide mononucleotide (NMN): The current evidence. Nutrients, 10(12), 1450.

[3] Johnson, S., Imai, S. I. (2024). NAD + biosynthesis, recycling, and compartmentalization: Implications for aging and preventative medicine. Trends in Cell Biology, 34(1), 75-97.

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Verified reviews from longtails.com

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4.9
Rated 4.9 out of 5 stars
Based on 7 reviews
Total 5 star reviews: 6
Total 4 star reviews: 1
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7 reviews
  • KS
    KRISTA S. C.
    Verified Buyer
    I recommend this product
    How old is your dog(s)? 5, 3
    What is your dog(s) size? Large, Extra Large
    What are your health concerns? Healthy Aging, Energy & Vitality, Mobility & Joint Health, Metabolism, Healthy Skin
    Rated 5 out of 5 stars
    1 year ago
    Not sure who loves it more!

    I have the 3 pickiest dog eaters ever and I usually have to get more clever than I want to when trying to get any of them to take a supplement. They needed no convincing with this, they loved it and got so excited when they heard me open the container! I got 1 container and was mostly giving it to my 5 yr old Rhodesian Ridgeback but then also started my Dutch Shepherd on it because he injured his knee playing. We started on a second container and that's when I noticed the changes. I am a skeptic through and through I'm science driven and don't believe anything until I'm convinced with evidence and supporting real life examples and let me tell you.. I'm convinced my Rhodesian doesn't nap as much wants to play ball like he did when he was a puppy and just seems to be over all waggier and smileier! It's wild, we are out of the supplement for now and the benefits seem to remain even though I haven't given it to him in over 2 weeks! The injury my Dutch Shepherd sustained was to a knee ligament and I was told that 6 weeks or more with zero activity would be a quick recovery. Anyone with a Dutch shep knows that there is no such thing as zero activity and both he and I were about to go crazy while limiting, as best I could, playing ball. I would say at best .. we mostly limited vigorous activity for a few weeks but still were active and then slowly added back some fetch and longer walks. With the addition of NAD+ i am quite confident we are where we are now because of it! I can…

  • TF
    Tatians F.
    Verified Buyer
    I recommend this product
    How old is your dog(s)? 7
    What is your dog(s) size? Large
    What are your health concerns? Healthy Aging, Energy & Vitality, Cognitive Function, General Wellness, Immune Support
    Rated 5 out of 5 stars
    1 year ago
    Can’t get enough!

    We began using this product about 2 months ago. Everyday she looks forward to her dinner bowl full of longtails goodness! Truthfully, she would eat the entire jar in one sitting if I let her. I’ve noticed her go from lounging around the house to a spry and alert pup. Her mood seems to have changed and she is now roughing and tumbling with her adopted bro, as they did when he was a pup. Thank god for long tails, she needs the energy to keep up with the various little people seeking her attention on the daily. I am so grateful to have found this product.

  • RG
    Remi G.
    Verified Buyer
    I recommend this product
    How old is your dog(s)? 16, 5
    What is your dog(s) size? Small
    What are your health concerns? Healthy Aging, Energy & Vitality, Mobility & Joint Health, Cognitive Function, Immune Support
    Rated 5 out of 5 stars
    12 seconds ago
    Long tails NAD

    Works great for my 16 year old chihuahua big difference in pep also works for my 5 year old Maltese . Highly recommend

  • MF
    Margaret F.
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    I recommend this product
    How old is your dog(s)? 16
    What is your dog(s) size? Medium
    What are your health concerns? Cognitive Function, Healthy Aging, Energy & Vitality, Mobility & Joint Health, General Wellness
    Rated 4 out of 5 stars
    2 months ago
    Nad

    She seems more active

  • ME
    Mariann E.
    Verified Buyer
    I recommend this product
    How old is your dog(s)? 11
    What is your dog(s) size? Extra Large
    What are your health concerns? Healthy Aging, Energy & Vitality, Mobility & Joint Health, Metabolism
    Rated 5 out of 5 stars
    1 year ago
    My dogs loved this

    It’s normally hard to get my dogs to take a supplement, but they loved LongTails. Thank you so much for making this great supplement.