James Field (Jame) - Own work Ginkgo biloba leaves with black background  CC BY-SA 3.0

Ginkgo Biloba: An Ancient Herb with Promising Benefits for Your Dog's Brain Health and Well-Being

Ozzy Fitoria

As devoted dog owners, we're always on the lookout for natural ways to support our furry friends' health and happiness, especially as they enter their golden years. One supplement that has gained attention for its potential cognitive and overall health benefits is Ginkgo biloba extract. Derived from the leaves of the ancient Ginkgo tree, this herbal remedy has been used in traditional medicine for centuries. Now, modern research is exploring how Ginkgo biloba may help our canine companions thrive. Let's dive into what the science says about the potential benefits of this fascinating herb for dogs.

What is Ginkgo Biloba Extract?

Ginkgo biloba is one of the oldest living tree species, with a history dating back over 200 million years. The extract from its fan-shaped leaves contains a complex mix of bioactive compounds, including flavonoids and terpenoids. These constituents are thought to be responsible for Ginkgo's various health-promoting properties, particularly its antioxidant and circulatory effects.1

Potential Benefits of Ginkgo Biloba for Dogs

While research on Ginkgo biloba specifically in dogs is still emerging, studies in other animals and humans suggest several potential benefits that may extend to our canine companions:

1. Brain and Neurological Research

Ginkgo biloba is studied for effects on brain tissue and neurological measures. This research is in humans, rodents or cell culture. No canine trial has tested it. Animal studies have shown that Ginkgo extract can enhance brain function by upregulating genes associated with neuronal health and neurotransmitter systems.2,3 These neuroprotective effects may be particularly valuable for senior dogs facing age-related cognitive decline.

In a study on aged beagles, a nutraceutical supplement containing Ginkgo biloba, phosphatidylserine, vitamin E, and pyridoxine significantly improved short-term memory performance compared to a control group.4 Another study found that Ginkgo extract reduced age-related behavioral disturbances in elderly dogs, potentially improving their quality of life.5

2. Promoting Cardiovascular Health

Ginkgo biloba's circulatory benefits may also extend to cardiovascular health. The herb's ability to enhance peripheral and cerebral blood flow is thought to contribute to its therapeutic potential for vascular disorders.6 In a study on dogs undergoing coronary occlusion and reperfusion, Ginkgo extract effectively prevented early ventricular fibrillation induced by reperfusion, suggesting potential cardioprotective effects.7

3. Other Research Areas

Ginkgo biloba has also been examined in relation to antioxidant activity. This research is in humans, rodents or cell culture. No canine trial has tested it. A study on hybrid groupers found that Ginkgo leaf extract supplementation improved immunity, intestinal health, and antioxidant ability in fish fed high-fat diets.8 While the specific effects may vary between species, these findings suggest Ginkgo could help support overall health and resilience in dogs as well.

Additionally, Ginkgo extract has shown protective effects against lung injury in dogs undergoing hypothermic cardiopulmonary bypass, possibly by reducing systemic inflammation.9 This highlights its potential to support dogs facing various health challenges.

Is Ginkgo Biloba Safe for Dogs?

Ginkgo biloba is generally considered safe for consumption, with a long history of use in humans and few reported side effects.10 However, it's essential to note that most safety studies have been conducted in humans or laboratory animals, with limited data specifically on dogs.

As with any new supplement, it's crucial to consult with your veterinarian before giving Ginkgo biloba to your dog. They can help you determine if it's appropriate for your individual dog's needs, health status, and any medications they may be taking. Your vet can also guide you on proper dosage and brand selection.

When choosing a Ginkgo biloba supplement for your dog, opt for a high-quality product from a reputable company that specializes in pet supplements. Look for extracts that are standardized to contain consistent levels of active compounds and are free from contaminants or fillers.

The Bottom Line

Ginkgo biloba extract is a promising natural supplement that may offer cognitive, cardiovascular, and overall health benefits for dogs. While more canine-specific research is needed to fully understand its effects and optimal use, the available evidence from animal and human studies suggests it could be a valuable addition to a holistic wellness plan for our furry friends.

As always, work closely with your veterinarian when considering any new supplement for your dog. With their guidance and a commitment to quality sourcing, Ginkgo biloba may be a natural way to support your dog's brain health, resilience, and vitality throughout their life.

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A note on what we actually sell

LongTails does not make a Ginkgo biloba supplement, and this article is not selling you one. Our formula contains no Ginkgo biloba. LongTails NAD+ Precursor is built on 200 mg of nicotinamide riboside plus 1,500 mg of hydrolyzed collagen per scoop, both printed on the label with no proprietary blend. Different compound, different purpose.

If you came here researching Ginkgo biloba specifically, buy it from a supplier your veterinarian trusts and ask them about dosing for your dog. If what brought you here is the broader question of cellular support in an aging dog, that is the area we do work in, and our guide to NAD+ for dogs covers what the research does and does not show.

References:

  1. Mahadevan, S., & Park, Y. (2008). Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. Journal of food science, 73(1), R14-R19. https://consensus.app/papers/multifaceted-benefits-ginkgo-biloba-chemistry-efficacy-mahadevan/a59c4ccfd043567ba0d8bda1b19556dc/

  2. Watanabe, C. M., Wolffram, S., Ader, P., Rimbach, G., Packer, L., Maguire, J. J., ... & Gohil, K. (2001). The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba. Proceedings of the National Academy of Sciences, 98(12), 6577-6580. https://consensus.app/papers/effects-medicine-ginkgo-biloba-watanabe/51e2a52bc3355fc985dcb4e859530e04/

  3. Ahlemeyer, B., & Krieglstein, J. (2003). Neuroprotective effects of Ginkgo biloba extract. Cellular and Molecular Life Sciences CMLS, 60(9), 1779-1792. https://consensus.app/papers/effects-ginkgo-biloba-extract-ahlemeyer/b7562b41d65d5cd7bb308a7d7d079a42/

  4. Araujo, J. A., Landsberg, G. M., Milgram, N. W., & Miolo, A. (2008). Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. The Canadian veterinary journal, 49(4), 379. https://consensus.app/papers/memory-performance-aged-beagles-supplement-containing-araujo/143f1411e03d5634bc11cf569dc52701/

  5. Reichling, J., Frater-Schröder, M., Herzog, K., Bucher, S., & Saller, R. (2006). Reduction of behavioural disturbances in elderly dogs supplemented with a standardised Ginkgo leaf extract. Schweizer Archiv fur Tierheilkunde, 148(5), 257-263. https://consensus.app/papers/reduction-disturbances-dogs-supplemented-ginkgo-leaf-reichling/ee60b55764a753d18595dbaab95eccbd/

  6. McKenna, D. J., Jones, K., & Hughes, K. (2001). Efficacy, safety, and use of ginkgo biloba in clinical and preclinical applications. Alternative therapies in health and medicine, 7(5), 70-90. https://consensus.app/papers/efficacy-safety-ginkgo-preclinical-applications-mckenna/61540eb150f05be6a5dea9da68eece4d/

  7. Lo, H. M., Lin, F. Y., Tseng, C. S., Chiang, F. T., Hsu, K. L., & Tseng, Y. Z. (1994). Effect of EGb 761, a ginkgo biloba extract, on early arrhythmia induced by coronary occlusion and reperfusion in dogs. Journal of the Formosan Medical Association, 93, 643-648. https://consensus.app/papers/effect-ginkgo-biloba-extract-arrhythmia-induced-lo/c23398d5f7d45b8fa53c8edd214c4aaa/

  8. Tan, X., Sun, Z., & Ye, C. (2020). Dietary Ginkgo biloba leaf extracts supplementation improved immunity and intestinal morphology, antioxidant ability and tight junction proteins mRNA expression of hybrid groupers (Epinephelus lanceolatus ♂× Epinephelus fuscoguttatus ♀) fed high lipid diets. Fish & shellfish immunology, 97, 403-412. https://consensus.app/papers/dietary-ginkgo-biloba-leaf-extracts-supplementation-tan/e44b4ee7d6345df489a000b4add3d8a2/

  9. Deng, Q., Deng, Y. K., & An, Y. W. (2012). Protective effects of Ginkgo biloba extract on the lung injury of dogs undergoing hypothermic cardiopulmonary bypass. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi= Chinese journal of integrated traditional and Western medicine, 32(9), 1217-1220. https://consensus.app/papers/effects-ginkgo-biloba-extract-injury-dogs-undergoing-deng/f085ec8e44fc51e7a1e20c711052b278/

  10. Mahadevan, S., & Park, Y. (2008). Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. Journal of food science, 73(1), R14-R19. https://consensus.app/papers/multifaceted-benefits-ginkgo-biloba-chemistry-efficacy-mahadevan/a59c4ccfd043567ba0d8bda1b19556dc/

This article is for informational purposes only. It is not, nor is it intended to be, a substitute for professional medical or veterinary advice, diagnosis, or treatment and should never be relied upon or perceived as specific medical or veterinary advice.

We recognize there may be different points of view or opinions on some aspect or even the premise of this article. Our goal at LongTails is to provide the best, clearest, and most helpful information possible to help keep your dog happy, healthy and safe.

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    I have the 3 pickiest dog eaters ever and I usually have to get more clever than I want to when trying to get any of them to take a supplement. They needed no convincing with this, they loved it and got so excited when they heard me open the container! I got 1 container and was mostly giving it to my 5 yr old Rhodesian Ridgeback but then also started my Dutch Shepherd on it because he injured his knee playing. We started on a second container and that's when I noticed the changes. I am a skeptic through and through I'm science driven and don't believe anything until I'm convinced with evidence and supporting real life examples and let me tell you.. I'm convinced my Rhodesian doesn't nap as much wants to play ball like he did when he was a puppy and just seems to be over all waggier and smileier! It's wild, we are out of the supplement for now and the benefits seem to remain even though I haven't given it to him in over 2 weeks! The injury my Dutch Shepherd sustained was to a knee ligament and I was told that 6 weeks or more with zero activity would be a quick recovery. Anyone with a Dutch shep knows that there is no such thing as zero activity and both he and I were about to go crazy while limiting, as best I could, playing ball. I would say at best .. we mostly limited vigorous activity for a few weeks but still were active and then slowly added back some fetch and longer walks. With the addition of NAD+ i am quite confident we are where we are now because of it! I can…

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